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糖尿病及并發(fā)癥研究
Diabetes And Complications項(xiàng)目背景:
C57雄性小鼠是構(gòu)建糖尿病視網(wǎng)膜病變小鼠的常用模型,利用小劑量多次腹腔注射STZ誘導(dǎo)糖尿病,較好的模擬了2型糖尿病的發(fā)病過(guò)程,發(fā)生的視網(wǎng)膜血管病變也比較經(jīng)典,此外,db/db小鼠也是研究糖尿病誘導(dǎo)的視網(wǎng)膜變性和檢測(cè)視神經(jīng)保護(hù)藥物的潛在機(jī)制的合適模型。
展示案例:
HE染色檢測(cè)糖尿病視網(wǎng)膜病變小鼠視網(wǎng)膜病變情況
參考文獻(xiàn):
Amelioration of diabetic retinopathy in db/db mice by treatment with different proportional three active ingredients from Tibetan medicine Berberis dictyophylla F.
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